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Dimethyl fumarate and alopecia

The Netherlands Pharmacovigilance Centre Lareb has received 92 cases about alopecia associated with the use of dimethyl fumarate. Alopecia is not described in t...

Anastrozole and depressed mood

The Netherlands Pharmacovigilance Centre Lareb received 14 reports of depressed mood associated with the use of anastrozole (Arimedex®). In the Summary of Prod...

Patient organizations can help enable effective communication of adverse drug reactions

To improve therapeutic decision making, it is crucial that information regarding adverse drug reaction...

Preparation started to monitor the safety and efficacy COVID-19 vaccines

An European project has been started to prepare for the monitoring of the safety and efficacy of COVID-19 vaccines. Th...

Burden of adverse drugs reactions with biologics

Infections and musculoskeletal complaints are adverse drug reactions (ADRs) with the highest burden for the patient, while injection site reac...

Flucloxacillin and oesophageal complaints

The Netherlands Pharmacovigilance Centre Lareb received 22 reports of oesophageal complaints associated with the use of flucloxacillin. The complaint...

Psychiatric adverse drug reactions in the paediatric population

Psychiatric adverse drug reactions (ADRs) are common in the paediatric population. 15% of ADRs in children reported to the Neth...

Diabetic ketoacidosis with dapagliflozin and carbohydrate-restricted diet

Dapagliflozin should not be administrated to patients with an increased risk for diabetic ketoacidosis, for example p...

Prevent oesophagitis when using dabigatran

Oesophagitis is a known adverse drug reaction (ADR) of the direct acting oral anticoagulant dabigatran (Pradaxa®). The Netherlands Pharmacovigilance...