News updates

ACE-inhibitors and psoriasis

The Netherlands Pharmacovigilance Centre Lareb received 25 reports of aggravation of psoriasis or new-onset psoriasis in association with Angiotensin Converting E...

Increased number of adverse drug reactions associated with oxaliplatin

During the last year, the Netherlands Pharmacovigilance Centre Lareb sees an increase in the number of reports of advers...

Noscapine and angioedema

Noscapine is an Over-The-Counter (OTC) drug. It is used as treatment of (a nonproductive) tickling cough and is also the drug of first choice when a cough depressant ...

Isotretinoin (Roaccutane) and erectile dysfunction

Isotretinoin is used as a treatment for severe types of acne, that prove resistant to standard therapy. Lareb received 7 reports on erectile...

Selective serotonergic vasoconstrictors (triptans) and pain re-activation

The Netherlands Pharmacovigilance Centre Lareb received 19 reports of pain re-activation in association with selectiv...

Fluconazole and Fixed Drug Eruption

Lareb received 13 reports of fixed drug eruptions (FDE) in association with fluconazole. Fluconazole is used in fungal infections, including Candida. A Fix...

The first Lareb conference on patient reporting was held on April 23-24 in Leiden, the Netherlands

The conference was attended by 60 participants from 21 different counties. During the confer...

Good healthcare requires more attention for adverse drug reactions

Adverse Drug Reactions (ADRs) can have a major impact on the health and well-being of patients. Unfortunately, sufficient at...

ACE-inhibitors and hallucinations

The Netherlands Pharmacovigilance Centre Lareb received 15 reports of hallucinations associated with the use of ACE-inhibitors. ACE-inhibitors involved were ...